Pax6-Cre
Product ID:
C001279
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Retinal and panCreatic primordial cells, etc.
Product Type
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Genotype
Sex
Quantity
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Basic Information
Model Name
Pax6-Cre
Product ID
C001279
Gene Name
Background
C57BL/6JCya
Gene Alias
Dey; Sey; AEY11; Pax-6; Gsfaey11; 1500038E17Rik
Classification
Cre Driver Lines
NCBI ID
Phenotype
Chromosome
2
Document
Note: When using this mouse strain in a publication, please cite “Pax6-Cre mice (Catalog C001279) were purchased from Cyagen.”
Strain Description
This strain was constructed using gene editing technology. The TAA stop codon was replaced with the “P2A-Cre” cassette. The expression pattern of Cre recombinase in these mice is similar to that of the endogenous Pax6 gene. When crossed with mice containing loxP sites, sequence deletion between loxP sites mediated by Cre recombinase occurs in the retina during the early embryonic development of the offspring. The heterozygous Pax6-Cre mice are viable and fertile, while homozygous mice have incomplete eye development.
Validation Data