This strain was constructed using gene editing technology. The TAA stop codon was replaced with the “P2A-Cre” cassette. The expression pattern of Cre recombinase in these mice is similar to that of the endogenous Pax6 gene. When crossed with mice containing loxP sites, sequence deletion between loxP sites mediated by Cre recombinase occurs in the retina during the early embryonic development of the offspring. The heterozygous Pax6-Cre mice are viable and fertile, while homozygous mice have incomplete eye development.