Cyp19a1-IRES-Cre
Product ID:
C001382
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Ovarian granulocytes
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
Cyp19a1-IRES-Cre
Product ID
C001382
Gene Name
Background
C57BL/6JCya
Gene Alias
Ar; ArKO; Int5; Cyp19; Int-5; p450arom
Classification
Cre Driver Lines
NCBI ID
Phenotype
Chromosome
9
Document
Note: When using this mouse strain in a publication, please cite “Cyp19a1-IRES-Cre mice (Catalog C001382) were purchased from Cyagen.”
Strain Description
The Cyp19a1-IRES-Cre mice were constructed using gene editing technology to insert an IRES-Cre element downstream of the stop codon of the endogenous Cyp19a1 gene in mice. The expression pattern of Cre recombinase is similar to that of the endogenous gene and does not affect its normal expression. When this strain is crossed with mice containing loxP sites, sequence recombination between loxP sites mediated by Cre recombinase can occur in the granulosa cells of the ovaries of offspring mice.
Validation Data