Nppa-Cre
Product ID:
C001478
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Cardiomyocytes
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Basic Information
Model Name
Nppa-Cre
Product ID
C001478
Gene Name
Background
C57BL/6JCya
Gene Alias
ANP; Anf; CDD; Pnd
Classification
Cre Driver Lines
NCBI ID
Phenotype
Chromosome
4
Document
Note: When using this mouse strain in a publication, please cite “Nppa-Cre mice (Catalog C001478) were purchased from Cyagen.”
Strain Description
This strain was constructed using gene editing technology. Part of the exon 1 coding sequence was replaced with the “Cre-rBG pA” cassette. Nppa-Cre mice can specifically express Cre recombinase in ventricular and atrial cardiomyocytes. When this strain is crossed with mice containing loxP sites, the offspring can produce sequence recombination between loxP sites mediated by Cre recombinase in cardiomyocytes. The heterozygous Nppa-Cre mice are viable and fertile.
Validation Data