Lyz2-IRES-CreERT2
Product ID:
C001499
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Bone marrow cell lineage (monocytes, mature macrophages and granulocytes)
Product Type
Age
Genotype
Sex
Quantity
Price:
Contact for Pricing
Basic Information
Model Name
Lyz2-IRES-CreERT2
Product ID
C001499
Gene Name
Background
C57BL/6JCya
Gene Alias
Lys; Lzm; Lzp; Lysm; Lyzs; Lyzf2; Lzm-s1
Classification
Cre Driver Lines
NCBI ID
Phenotype
Chromosome
10
Document
Note: When using this mouse strain in a publication, please cite “Lyz2-IRES-CreERT2 mice (Catalog C001499) were purchased from Cyagen.”
Strain Description
Lyz2-IRES-CreERT2 mice were generated using gene editing technology to integrate the tamoxifen-inducible CreERT2 recombinase expression element into the 3’UTR of the mouse Lyz2 gene. This mimics the expression pattern of the endogenous gene while maintaining Lyz2 expression. When bred with mice carrying a loxP site-flanked sequence, Cre recombinase-mediated recombination of the flanked sequence occurs in myeloid cells, including monocytes, mature macrophages, and granulocytes, following tamoxifen induction.
Validation Data