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B6-hGPR75 (1)
Product ID:
C001613
Background:
C57BL/6JCya
Documents:
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Strain Description
The B6-hGPR75 (1) mouse is a humanized model generated through gene editing technology, in which part of the mouse Gpr75 gene sequence is replaced in situ with the human GPR75 gene sequence. Homozygous B6-hGPR75 (1) mice are viable and fertile. This model can be used to study the pathological mechanisms and therapeutic interventions for obesity, metabolic diseases, and cardiovascular diseases, as well as for screening, developing, and evaluating the safety of GPR75-targeted drugs.
Application Area
Area
GPR75-targeted drug screening, development, and evaluation
Area
Research on the pathological mechanisms and therapeutic approaches of obesity, metabolic syndrome, cardiovascular disease, and cancer
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