H11-Trem2-iCre
Product ID:
C001677
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Microglia, macrophages, osteoclasts, dendritic cells, monocytes, and Trem2-positive cells
Product Type
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Basic Information
Model Name
H11-Trem2-iCre
Product ID
C001677
Gene Name
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Background
C57BL/6JCya
Gene Alias
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Classification
Cre Driver Lines
NCBI ID
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Phenotype
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Chromosome
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More
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Document
Note: When using this mouse strain in a publication, please cite “H11-Trem2-iCre mice (Catalog C001677) were purchased from Cyagen.”
Strain Description
The “Mouse Trem2 promoter-Kozak-iCre-WPRE-BGH pA” cassette was inserted into H11 locus (~0.7 kb 5' of Eif4enif1 gene and ~4.5 kb 3' of the Drg1 gene). Cre recombinase is expressed under the regulatory control of Trem2 promoter, without impacting the endogenous expression of the other genes.
Validation Data