B6-hIL17F
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
B6-hIL17F
Product ID
C001715
Gene Name
Background
C57BL/6NCya
Gene Alias
ML1; ML-1; IL17A; CANDF6; IL-17F
Classification
Cytokine Humanized Models,Full-Gene Humanized Models,Autoimmune Disease Models
NCBI ID
Phenotype
Chromosome
6
Document
Note: When using this mouse strain in a publication, please cite “B6-hIL17F mice (Catalog C001715) were purchased from Cyagen.”
Strain Description
The B6-hIL17F mouse is a humanized model constructed by replacing the sequence of the mouse Il17f gene in situ with the corresponding sequence from the human IL17F gene. The B6-hIL17F mice can be used for studies on psoriasis, rheumatoid arthritis, inflammatory bowel disease, and pathogenesis of inflammatory disorders, as well as for IL17F-targeted drug development.
Application Area
IL17F-targeted drug screening, development, and evaluation
Research on the pathological mechanisms and therapeutic approaches of psoriasis, rheumatoid arthritis, and inflammatory bowel disease
Research on other inflammatory disorders
Validation Data