B6-hIL17F
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Strain Description
The B6-hIL17F mouse is a humanized model constructed by replacing the sequence of the mouse Il17f gene in situ with the corresponding sequence from the human IL17F gene. The B6-hIL17F mice can be used for studies on psoriasis, rheumatoid arthritis, inflammatory bowel disease, and pathogenesis of inflammatory disorders, as well as for IL17F-targeted drug development.
Application Area
IL17F-targeted drug screening, development, and evaluation
Research on the pathological mechanisms and therapeutic approaches of psoriasis, rheumatoid arthritis, and inflammatory bowel disease
Research on other inflammatory disorders
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