RCL-tdTomato
Product ID:
C001742
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Systemic
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Basic Information
Model Name
RCL-tdTomato
Product ID
C001742
Gene Name
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Background
C57BL/6JCya
Gene Alias
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Classification
Reporter Mouse Lines
NCBI ID
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Phenotype
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Chromosome
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More
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Document
Note: When using this mouse strain in a publication, please cite “RCL-tdTomato mice (Catalog C001742) were purchased from Cyagen.”
Strain Description
RCL-tdTomato mice are generated via genome editing to knock the CAG-LSL-tdTomato cassette into the ROSA26 safe harbor locus. Upstream of the tdTomato gene lies a loxP-Stop-loxP (LSL) cassette, which blocks the transcription and expression of tdTomato. Upon Cre recombination, cells expressing Cre recombinase (and their future cell lineages) exhibit strong tdTomato fluorescence. This model is suitable for validating Cre mice with high recombination efficiency and potential expression leakage, as well as for other cell lineage tracing applications.
Validation Data