Fcrls-CreERT2-EGFP
Product ID:
C001752
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Microglia, macrophages, central nervous system, and Fcrls-positive cells
Product Type
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Basic Information
Model Name
Fcrls-CreERT2-EGFP
Product ID
C001752
Gene Name
Background
C57BL/6JCya
Gene Alias
IgSR; Msr2; Fcrh2; Fcrls; IFGP2; MMAN-g; FcRH2sc; moFcRH2sc; 9330158F12; 2810439C17Rik
Classification
Cre Driver Lines,Reporter Mouse Lines
NCBI ID
Phenotype
Chromosome
3
Document
Note: When using this mouse strain in a publication, please cite “Fcrls-CreERT2-EGFP mice (Catalog C001752) were purchased from Cyagen.”
Strain Description
The IRES-CreERT2-P2A-EGFP-WPRE-BGH pA cassette was inserted 60~100bp downstream of the TGA stop codon. CreERT2 recombinase and enhanced green fluorescent protein (EGFP) are expressed under the regulatory control of Fcrls gene elements. This model is a Tamoxifen-inducible Cre mouse, and when crossed with mice containing loxP sites, the offspring mice are expected to undergo sequence recombination between loxP sites mediated by Cre recombinase in Fcrls-positive cells following Tamoxifen induction. In addition to studies of Cre recombinase-mediated gene recombination, this model can also be used for EGFP fluorescent protein tracing studies.
Validation Data