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Trhr-iCre
Product ID:
C001766
Background:
C57BL/6JCya
Documents:
Click here to download >
Expressing Tissues/Cells:
Anterior pituitary, hypothalamus, cerebral cortex, hippocampus, amygdala, and Trhr-positive cells
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Strain Description
Trhr-iCre mice are generated via genome editing by inserting a P2A-iCre cassette upstream of the TAA stop codon in the mouse Trhr gene, enabling iCre recombinase (codon-optimized Cre) expression under the control of endogenous Trhr regulatory elements. The expression pattern of iCre recombinase mirrors that of the endogenous Trhr gene. When crossed with mice containing loxP sites, Cre-mediated recombination between loxP sites is expected to occur in Trhr-positive cells of the offspring.
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