Zc3hav1-mCherry-iCre
Product ID:
C001771
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Thymus, spleen, and other tissues, as well as Zc3hav1-positive cells
Product Type
Age
Genotype
Sex
Quantity
Price:
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Basic Information
Model Name
Zc3hav1-mCherry-iCre
Product ID
C001771
Gene Name
Background
C57BL/6JCya
Gene Alias
ZAP; ARTD13; PARP13; D6Bwg1452e; 1200014N16Rik; 2900058M19Rik; 9130009D18Rik; 9830115L13Rik
Classification
Cre Driver Lines,Reporter Mouse Lines
NCBI ID
Phenotype
Chromosome
6
Document
Note: When using this mouse strain in a publication, please cite “Zc3hav1-mCherry-iCre mice (Catalog C001771) were purchased from Cyagen.”
Strain Description
Zc3hav1-mCherry-iCre mice are generated via genome editing by replacing the TAG stop codon of the mouse Zc3hav1 gene with a P2A-mCherry-T2A-iCre cassette, enabling co-expression of iCre recombinase (codon-optimized Cre) and mCherry under the control of endogenous Zc3hav1 regulatory elements. The expression pattern of iCre recombinase mirrors that of the endogenous Zc3hav1 gene. When crossed with mice containing loxP sites, Cre-mediated recombination between loxP sites is expected to occur in Zc3hav1-positive cells of the offspring. Beyond Cre-loxP gene recombination, this model enables mCherry-based fluorescent tracing.
Validation Data