Il4 KO
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
Il4 KO
Product ID
C001818
Gene Name
Background
C57BL/6JCya
Gene Alias
Il-4; BSF-1
Classification
Other Disease Models
NCBI ID
Phenotype
Chromosome
11
Document
Note: When using this mouse strain in a publication, please cite “Il4 KO mice (Catalog C001818) were purchased from Cyagen.”
Strain Description
The Il4 KO mouse, a gene knockout model generated by deleting exons 1–4 of the murine Il4 gene (homologous to human IL4), serves as a valuable tool for investigating the pathogenesis of allergic disorders (e.g., asthma, atopic dermatitis, allergic rhinitis), anti-parasitic immunity, and specific cancers, as well as for developing related therapeutic strategies.
Application Area
Pathogenesis and therapeutic evaluation of allergic diseases (e.g., asthma, atopic dermatitis, allergic rhinitis)
Construction of anti-parasitic infection models and dissection of defense mechanisms
Regulatory mechanisms of Th1/Th2 immune balance
Modulation of tumor immune microenvironment and development of immunotherapeutic strategies
Validation Data