RCL-GCaMP6f
Product ID:
I001028
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Calcium binding (e.g. neuronal activation)
Product Type
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Basic Information
Model Name
RCL-GCaMP6f
Product ID
I001028
Gene Name
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Background
C57BL/6JCya
Gene Alias
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Classification
Reporter Mouse Lines
NCBI ID
--
Phenotype
Chromosome
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More
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Document
Note: When using this mouse strain in a publication, please cite “RCL-GCaMP6f mice (Catalog I001028) were purchased from Cyagen.”
Strain Description
This model conditionally overexpresses the GCaMP6f gene in the Rosa26 safe harbor in the mouse genome and is a Cre-dependent fluorescent calcium indicator strain. The presence of a loxP-Stop-loxP element upstream of the GCaMP6f gene expression element blocks GCaMP6f expression. Upon mating with Cre mice, Cre-mediated sequence recombination between loxP sites results in the deletion of the Stop element in the offspring mice, and bright EGFP fluorescence is observed following calcium binding (e.g. neuronal activation).
Validation Data