Ins1-CreERT2
Product ID:
I001151
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Pancreatic β cells
Product Type
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Genotype
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Basic Information
Model Name
Ins1-CreERT2
Product ID
I001151
Gene Name
Background
C57BL/6JCya
Gene Alias
Ins-1; Ins2-rs1
Classification
Cre Driver Lines
NCBI ID
Phenotype
Chromosome
19
Document
Note: When using this mouse strain in a publication, please cite “Ins1-CreERT2 mice (Catalog I001151) were purchased from Cyagen.”
Strain Description
The partial coding region of exon 2 of the mouse Ins1 gene was replaced with the "Kozak-CreERT2-WPRE-BGH pA" cassette. CreERT2 recombinase is expressed under the regulatory control of Ins1 gene elements. This model is a Tamoxifen-inducible Cre mouse, and when crossed with mice containing loxP sites, the offspring mice are expected to undergo sequence recombination between loxP sites mediated by Cre recombinase in the pancreas following T amoxifen induction.
Validation Data