Syn1-IRES-CreERT2
Product ID:
I001168
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Nervous system (higher expression in cortex, relatively less in the striatum), genitourinary system (higher expression in male germ cells than in female germ cells)
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Strain Description
The "IRES-CreERT2" cassette was inserted 22 bp downstream of the TGA stop codon. CreERT2 recombinase is expressed under the regulatory control of Syn1 gene elements. This model is a Tamoxifen-inducible Cre mouse, and when crossed with mice containing loxP sites, the offspring mice are expected to undergo sequence recombination between loxP sites mediated by Cre recombinase in cells such as neurons following Tamoxifen induction.
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