B6-htau/hGLP-1R
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Strain Description
The B6-htau/hGLP-1R mouse is obtained by mating B6-htau mice (Catalog No.: C001410) with B6-hGLP-1R mice (Catalog No.: C001421). This model can be used for research on neurodegenerative diseases such as frontotemporal dementia (FTD) and Alzheimer's disease (AD), as well as metabolic diseases such as obesity and type 2 diabetes. It is also useful for developing GLP-1 receptor agonist (GLP-1RA) drugs or for the preclinical evaluation of the potential therapeutic effects of GLP-1RA drugs in tauopathy-related diseases like Alzheimer's disease (AD).
Application Area
Research on neurodegenerative diseases such as frontotemporal dementia (FTD) and Alzheimer's disease (AD)
Research on metabolic diseases such as obesity and type 2 diabetes
Evaluation of the potential therapeutic effects of GLP-1 receptor agonist (GLP-1RA) drugs on Alzheimer's disease (AD)
Development of GLP-1RA drugs
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