Pdgfra-CreERT2 Rat
Product Name
Pdgfra-CreERT2 Rat
Product ID
IR001
Strain Name
SD-Pdgfraem1(Cre/ERT2)/Cya
Backgroud
Sprague-Dawley
Examples of Expressing Tissues/Cells
Oligodendrocyte Precursor Cells (OPC) or NG2+ Glial Cells in the Spinal Cord and Forebrain
When using this mouse strain in a publication, please cite “Pdgfra-CreERT2 Rat (Catalog IR001) were purchased from Cyagen.”
Product Type
Age
Genotype
Sex
Quantity
Gene Name
Gene Alias
APDGFR, PDGFACE
NCBI ID
Chromosome
Chr 14
MGI ID
Datasheet
Strain Description
The ATG start codon of the rat Pdgfra gene was replaced with the Kozak-CreERT2-WPRE-BGH pA cassette. When this strain is crossed with rats containing loxP sites, after the offspring are induced by tamoxifen, it is expected that Cre recombinase-mediated sequence recombination between loxP sites will occur in oligodendrocyte precursor cells (OPC) or NG2+ glial cells in the spinal cord and forebrain.
Strain Strategy
Figure 1. Gene editing strategy for Pdgfra-CreERT2 rats.
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