C57BL/6JCya-Mpiem1flox/Cya
Common Name:
Mpi-flox
Product ID:
S-CKO-00833
Background:
C57BL/6JCya
Product Type
Age
Genotype
Sex
Quantity
Price:
Contact for Pricing
Basic Information
Strain Name
Mpi-flox
Strain ID
CKOCMP-110119-Mpi-B6J-VA
Gene Name
Product ID
S-CKO-00833
Gene Alias
1110002E17Rik; Mpi-1; Mpi1
Background
C57BL/6JCya
NCBI ID
Modification
Conditional knockout
Chromosome
9
Phenotype
Document
Application
--
Note: When using this mouse strain in a publication, please cite “C57BL/6JCya-Mpiem1flox/Cya mice (Catalog S-CKO-00833) were purchased from Cyagen.”
Strain Description
Ensembl Number
ENSMUST00000034856
NCBI RefSeq
NM_025837
Target Region
Exon 3~5
Size of Effective Region
~2.7 kb
Detailed Document
Overview of Gene Research
Mpi, short for Mannose-6-phosphate isomerase, is an enzyme-encoding gene. Mannose-6-phosphate isomerase catalyzes the interconversion between fructose-6-phosphate and mannose-6-phosphate, which is crucial in the metabolism of carbohydrates and plays an important role in various cellular processes [1].
No information regarding KO/CKO mouse models or loss-of-function experiments was found in the provided references.
In conclusion, Mpi is essential for carbohydrate metabolism-related cellular processes. Although no mouse model-based disease-related contributions were presented in the references, understanding Mpi's function is important for elucidating normal cellular metabolism and potentially related disease mechanisms.
References：
1. Wang, Cheng, Yuan, Chuang, Wang, Yahui, Wei, Leyi, Hou, Qingzhen. . MPI-VGAE: protein-metabolite enzymatic reaction link learning by variational graph autoencoders. In Briefings in bioinformatics, 24, . doi:10.1093/bib/bbad189. https://pubmed.ncbi.nlm.nih.gov/37225420/
Quality Control Standard
Sperm Test
Pre-cryopreservation: Measurement of sperm concentration, determination of sperm viability.
Post-cryopreservation: A vial of cryopreserved sperms is selected for in-vitro fertilization from each batch.
Environmental Standards:SPF
Available Region:Global
Source:Cyagen