C57BL/6JCya-Or5ap2em1/Cya
Common Name:
Or5ap2-KO
Product ID:
S-KO-08020
Background:
C57BL/6JCya
Product Type
Age
Genotype
Sex
Quantity
Price:
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Basic Information
Strain Name
Or5ap2-KO
Strain ID
KOCMP-258573-Or5ap2-B6J-VA
Gene Name
Product ID
S-KO-08020
Gene Alias
MOR201-2; Olfr1020
Background
C57BL/6JCya
NCBI ID
Modification
Conventional knockout
Chromosome
2
Phenotype
Document
Application
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Note: When using this mouse strain in a publication, please cite “C57BL/6JCya-Or5ap2em1/Cya mice (Catalog S-KO-08020) were purchased from Cyagen.”
Strain Description
Ensembl Number
ENSMUST00000055840
NCBI RefSeq
NM_146580
Target Region
Exon 1
Size of Effective Region
~3.0 kb
Detailed Document
Overview of Gene Research
Or5ap2 is an odorant receptor gene. Odorant receptors play a crucial role in detecting odor molecules and are also involved in non-olfactory functions. They may participate in signaling pathways related to chemosensation and potentially have an impact on various biological processes [1].
In a study on dwarf yellow-feathered broiler chickens, when fed with a basal diet supplemented with fermented bamboo powder (FPB), the expression of Or5ap2 was detected in the gizzard, proventriculus, and small intestine. Its expression was stronger in the small intestines compared to the gizzard and proventriculus. The FPB diet led to changes in growth performance, gut health, and the activation of odorant receptors, suggesting that Or5ap2 might be involved in the related physiological responses triggered by FPB [1].
In conclusion, Or5ap2, as an odorant receptor gene, shows responsive expression in the digestive organs of broiler chickens in response to a specific diet. Its role in growth performance and gut health in chickens indicates its potential importance in these biological processes, which may provide insights for understanding the underlying mechanisms in poultry health and growth regulation [1].
References:
1. Malyar, Rahmani Mohammad, Wei, Quanwei, Hou, Linsong, Zhou, Weisheng, Shi, Fangxiong. 2024. Fermented bamboo powder activates gut odorant receptors, and promotes intestinal health and growth performance of dwarf yellow-feathered broiler chickens. In Poultry science, 103, 103570. doi:10.1016/j.psj.2024.103570. https://pubmed.ncbi.nlm.nih.gov/38484565/
Quality Control Standard
Sperm Test
Pre-cryopreservation: Measurement of sperm concentration, determination of sperm viability.
Post-cryopreservation: A vial of cryopreserved sperms is selected for in-vitro fertilization from each batch.
Environmental Standards:SPF
Available Region:Global
Source:Cyagen