C57BL/6NCya-Abhd18em1/Cya
Common Name:
Abhd18-KO
Product ID:
S-KO-08685
Background:
C57BL/6NCya
Product Type
Age
Genotype
Sex
Quantity
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Contact for Pricing
Basic Information
Strain Name
Abhd18-KO
Strain ID
KOCMP-269423-Abhd18-B6N-VA
Gene Name
Product ID
S-KO-08685
Gene Alias
2310068E01Rik; 3110057O12Rik
Background
C57BL/6NCya
NCBI ID
Modification
Conventional knockout
Chromosome
3
Phenotype
Document
Application
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Note: When using this mouse strain in a publication, please cite “C57BL/6NCya-Abhd18em1/Cya mice (Catalog S-KO-08685) were purchased from Cyagen.”
Strain Description
Ensembl Number
ENSMUST00000108077
NCBI RefSeq
NM_026622
Target Region
Exon 5~8
Size of Effective Region
~6.9 kb
Detailed Document
Overview of Gene Research
Abhd18, without common aliases mentioned, is potentially involved in muscle growth and development. Through pathway analysis, relevant pathways like ether lipid metabolism, cortisol synthesis and secretion, and calcium signaling pathways, which Abhd18 might be a part of, are known to play pivotal roles in muscle growth and development [1].
In a study analyzing muscle transcriptomes of bovine, porcine, and sheep using interpretable machine learning models, Abhd18 was identified as a specific candidate gene for cattle among the key genes (SHAP genes) potentially influencing muscle growth and development across the three species [1].
In conclusion, Abhd18 appears to be a gene of importance in muscle growth and development, especially in cattle. Its identification as a candidate gene in this cross-species muscle transcriptome study contributes to understanding the genetic mechanisms underlying muscle development, which may have implications for the meat industry in terms of enhancing muscle quality and growth efficiency [1].
References:
1. Guo, Yaqiang, Li, Shuai, Na, Rigela, Gu, Mingjuan, Zhang, Wenguang. 2024. Comparative Transcriptome Analysis of Bovine, Porcine, and Sheep Muscle Using Interpretable Machine Learning Models. In Animals : an open access journal from MDPI, 14, . doi:10.3390/ani14202947. https://pubmed.ncbi.nlm.nih.gov/39457877/
Quality Control Standard
Sperm Test
Pre-cryopreservation: Measurement of sperm concentration, determination of sperm viability.
Post-cryopreservation: A vial of cryopreserved sperms is selected for in-vitro fertilization from each batch.
Environmental Standards:SPF
Available Region:Global
Source:Cyagen