C57BL/6JCya-Dipk1aem1/Cya
Common Name
Dipk1a-KO
Product ID
S-KO-17171
Backgroud
C57BL/6JCya
Strain ID
KOCMP-67266-Dipk1a-B6J-VB
When using this mouse strain in a publication, please cite “Dipk1a-KO Mouse (Catalog S-KO-17171) were purchased from Cyagen.”
Product Type
Age
Genotype
Sex
Quantity
Basic Information
Strain Name
Dipk1a-KO
Strain ID
KOCMP-67266-Dipk1a-B6J-VB
Gene Name
Product ID
S-KO-17171
Gene Alias
2900024C23Rik, Fam69a
Background
C57BL/6JCya
NCBI ID
Modification
Conventional knockout
Chromosome
Chr 5
Phenotype
Datasheet
Application
--
Strain Description
Ensembl Number
ENSMUST00000031198
NCBI RefSeq
NM_026062
Target Region
Exon 3~5
Size of Effective Region
~6.5 kb
Overview of Gene Research
Dipk1a, also known as FAM69A, is a gene predicted to code for a protein kinase. It contains an EF-hand Ca(2 + )-binding domain within its kinase domain, suggesting it may function as a Ca(2 + )-dependent kinase. It is part of the FAM69 family, and genes in this family are implicated in several neurological disorders [1].
No relevant information about Dipk1a from KO/CKO mouse models or loss-of-function experiments was found in the provided references.
In conclusion, Dipk1a is predicted to be a Ca(2 + )-dependent kinase and is associated with neurological disorders. Although no model-based research findings specific to Dipk1a were in the references, understanding its potential role as a kinase may provide insights into the molecular mechanisms underlying related neurological conditions.
References:
1. Dudkiewicz, Małgorzata, Lenart, Anna, Pawłowski, Krzysztof. 2013. A novel predicted calcium-regulated kinase family implicated in neurological disorders. In PloS one, 8, e66427. doi:10.1371/journal.pone.0066427. https://pubmed.ncbi.nlm.nih.gov/23840464/
Quality Control Standard
Sperm Test
Pre-cryopreservation: Measurement of sperm concentration, determination of sperm viability.
Post-cryopreservation: A vial of cryopreserved sperms is selected for in-vitro fertilization from each batch.
Environmental Standards:SPF
Available Region:Global
Source:Cyagen
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