C57BL/6JCya-Pdclem1/Cya
Common Name:
Pdcl-KO
Product ID:
S-KO-19473
Background:
C57BL/6JCya
Product Type
Age
Genotype
Sex
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Basic Information
Strain Name
Pdcl-KO
Strain ID
KOCMP-67466-Pdcl-B6J-VC
Gene Name
Product ID
S-KO-19473
Gene Alias
1200011E13Rik; PhLP1
Background
C57BL/6JCya
NCBI ID
Modification
Conventional knockout
Chromosome
2
Phenotype
Document
Application
--
Note: When using this mouse strain in a publication, please cite “C57BL/6JCya-Pdclem1/Cya mice (Catalog S-KO-19473) were purchased from Cyagen.”
Strain Description
Ensembl Number
ENSMUST00000009174
NCBI RefSeq
NM_026176
Target Region
Exon 2~3
Size of Effective Region
~2.6 kb
Detailed Document
Overview of Gene Research
There is no information directly related to the gene Pdcl in the provided references. The references mainly focus on chemical reactions involving PdCl₂ complexes, such as thiol-disulfide exchange [1], cross-coupling reactions [2], and synthesis of various Pd-containing compounds [4-10], as well as the use of PNA-based dynamic combinatorial libraries (PDCL) in lectin screening [3].
Since no information about the gene Pdcl's function, associated pathways, or results from gene knockout models is available from these references, a complete review as per the requirements cannot be provided.
In conclusion, due to the lack of relevant information in the given references, the biological functions of the gene Pdcl and its contributions to disease areas remain unknown based on this set of references.
References：
1. Guo, Jimin, Zha, Jianjian, Zhang, Tao, Tan, Qitao, Xu, Bin. 2021. PdCl2/DMSO-Catalyzed Thiol-Disulfide Exchange: Synthesis of Unsymmetrical Disulfide. In Organic letters, 23, 3167-3172. doi:10.1021/acs.orglett.1c00858. https://pubmed.ncbi.nlm.nih.gov/33797269/
2. Xia, Qinqin, Shi, Shicheng, Gao, Pengcheng, Szostak, Roman, Szostak, Michal. 2021. [(NHC)PdCl2(Aniline)] Complexes: Easily Synthesized, Highly Active Pd(II)-NHC Precatalysts for Cross-Coupling Reactions. In The Journal of organic chemistry, 86, 15648-15657. doi:10.1021/acs.joc.1c02183. https://pubmed.ncbi.nlm.nih.gov/34619970/
3. Farrera-Soler, Lluc, Daguer, Jean-Pierre, Raunft, Patrick, Imberty, Anne, Winssinger, Nicolas. 2020. PNA-Based Dynamic Combinatorial Libraries (PDCL) and screening of lectins. In Bioorganic & medicinal chemistry, 28, 115458. doi:10.1016/j.bmc.2020.115458. https://pubmed.ncbi.nlm.nih.gov/32241620/
Quality Control Standard
Sperm Test
Pre-cryopreservation: Measurement of sperm concentration, determination of sperm viability.
Post-cryopreservation: A vial of cryopreserved sperms is selected for in-vitro fertilization from each batch.
Environmental Standards:SPF
Available Region:Global
Source:Cyagen