Pamphlet
NKG Immunodeficient Mice
This pamphlet introduces Cyagen’s NKG immunodeficient mice and their variants, detailing immune features, research applications, validation data, and case studies for use in tumor, immune, and drug development research.
Overview
NKG mice, developed by Cyagen through Il2rg gene knockout on the NOD-Scid background, exhibit severe immunodeficiency with minimal T, B, and NK cells, low GvHD incidence, and extended survival. This pamphlet presents their sub-strains, immune reconstruction models, tumor application data, and real-world research cases in oncology, immunology, autoimmunity, and PDX/CDX model development.
Key Insights
Discover how NKG immunodeficient mice empower humanized model development and preclinical drug research.
- Key features of NKG mice and their immunodeficient profiles
- Functional comparisons across major NKG sub-strains
- Data on immune reconstitution and tumor model applications
- Real-world case studies in oncology, autoimmunity and GvHD
- FAQs on model use, immune leakage, and transplantation methods
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