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NKG-SGM3
Product ID:
I001177
Background:
NKG
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Strain Description
NKG-SGM3 mice constructed by integrating human KITLG, CSF2, and IL3 genes into the genome of NKG mice can effectively enhance myeloid differentiation and improve the transplantation efficiency of hematopoietic and acute myeloid leukemia cells and thus are valuable for immuno-oncology, immunology, and infectious disease research.
Application Area
Area
Construction of an immune system humanized mouse model supporting stable engraftment of myeloid lineages and regulatory T cell populations
Area
Research on the human immune system, hematopoietic systems, such as acute myeloid leukemia (AML)
Area
Human-derived cell line xenograft (CDX) and patient-derived xenograft (PDX)
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