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B6-hINHBE/ob
Product ID:
C001600
Background:
C57BL/6NCya;C57BL/6JCya
Documents:
Click here to download >
Product Type
Age
Genotype
Sex
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Price:
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Basic Information
Model Name
B6-hINHBE/ob
Product ID
C001600
Gene Name
INHBE, Lep
Background
C57BL/6NCya;C57BL/6JCya
Gene Alias
ob; obese
Classification
Cytokine Humanized Models,Full-Gene Humanized Models,Metabolic Disease Models
NCBI ID
83729, 16846
Phenotype
MGI:109269, MGI:104663
Chromosome
12
More
Rare Disease Data Center >>
Document
Click here to download >>
Note
Note: When using this mouse strain in a publication, please cite “B6-hINHBE/ob mice (Catalog C001600) were purchased from Cyagen.”
Strain Description
The B6-hINHBE/ob mouse model, generated by mating B6-hINHBE mice (Catalog Number: C001533) with Lep KO (ob/ob) mice (Catalog Number: C001368), is a metabolic disease model. It can be used for research on obesity, type II diabetes, and metabolic diseases related to improper fat distribution and storage, and for the development of human INHBE-targeted therapies.
Application Area
Area
Research on the obesity and type II diabetes
Area
Research on the metabolic diseases associated with improper fat distribution and storage
Area
Development of human INHBE-targeted therapies
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