Mybpc3 KO
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
Mybpc3 KO
Product ID
C001609
Gene Name
Background
C57BL/6JCya
Gene Alias
--
Classification
Metabolic Disease Models
NCBI ID
Phenotype
Chromosome
2
Document
Note: When using this mouse strain in a publication, please cite “Mybpc3 KO mice (Catalog C001609) were purchased from Cyagen.”
Strain Description
The Mybpc3 KO mouse is a gene knockout model created using gene-editing techniques to knock out the coding sequence of the Mybpc3 gene (the homolog of the human MYBPC3 gene) in mice. This model is used to research the pathogenic mechanisms of hypertrophic cardiomyopathy (HCM) and develop related therapeutic strategies.
Application Area
Studies of myocardial contraction mechanisms and cardiac function
Research on hypertrophic cardiomyopathy (HCM) pathogenesis and therapeutic drug evaluation
Investigations into dilated cardiomyopathy (DCM) and other cardiomyopathies
Validation Data