B6-hCFTR*F508del
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Strain Description
This strain was developed by introducing the F508del mutation into the CFTR-humanized mouse model (Catalog Number: I001132), creating a humanized disease model. The introduction of the mutation results in the manifestation of CF-related phenotypes in mice, making it suitable for research into CF mechanisms and the screening, development, and evaluation of therapies targeting the CFTR F508del mutation.
Application Area
Research on Cystic Fibrosis (CF)
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