B6-hIL13
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
B6-hIL13
Product ID
C001634
Gene Name
Background
C57BL/6NCya
Gene Alias
P600; IL-13
Classification
Immune Target Humanized Models,Cytokine Humanized Models,Full-Gene Humanized Models,Autoimmune Disease Models
NCBI ID
Phenotype
Chromosome
5
Document
Note: When using this mouse strain in a publication, please cite “B6-hIL13 mice (Catalog C001634) were purchased from Cyagen.”
Strain Description
The B6-hIL13 mouse is a humanized model constructed using gene editing technology to replace the entire base sequence of the mouse Il13 gene in situ with the corresponding sequence from the human IL13 gene. This model can be used for studying the pathological mechanisms and therapeutic approaches of allergic and inflammatory diseases, and for the development of IL13-targeted drugs.
Application Area
IL13-targeted drug screening, development, and evaluation
Research on the pathological mechanisms and therapeutic approaches of allergic and inflammatory diseases
Validation Data