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B6-hIL23A/hIL12B
Product ID:
C001620
Background:
C57BL/6NCya
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Strain Description
B6-hIL23A&hIL12B mice are IL12B and IL23A double humanized mouse models obtained by mating IL12B humanized mouse models with IL23A humanized mouse models. They express human IL12B and IL23A genomic sequences under the control of mouse promoters. This model is capable of reproducing human IL-23 cytokines and is a valuable tool for studying immune-related diseases. In addition, this model also provides a powerful preclinical research platform for evaluating the efficacy and mechanism of therapeutic drugs targeting IL-23 cytokines.
Application Area
Area
IL23A/IL12B-targeted drug screening, development, and evaluation
Area
Research on the pathological mechanisms and therapeutic approaches of immune-related diseases
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