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B6-hUSH2A (E10-15)
Product ID:
C001554
Background:
C57BL/6JCya
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Strain Description
The B6-hUSH2A (E10-15) mouse model, in which the corresponding mouse Ush2a gene sequence was replaced with human USH2A exons 10 to 15 and their flanking regions, provides a valuable tool for studying USH pathogenesis and evaluating preclinical treatments. Homozygous B6-hUSH2A (E10-15) mice are viable and fertile, making them suitable for drug evaluation and disease modeling.
Application Area
Area
Investigation of the pathogenic mechanisms underlying Usher syndrome (USH) and preclinical evaluation of therapeutic drugs
Area
Development, screening, and preclinical evaluation of drugs targeting USH2A
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