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Research Trend
What Do You Know about the Quality Control of rAAV Virus?
May 02, 2022
The production and preparation of rAAV is a key and difficult point in gene therapy, because the packaging system and purification method of rAAV will influence the infection efficiency and the expression efficiency of the target gene, and ultimately affect the results. Read More >
Research Trend
A Method to Study the Mechanisms of Gene Regulation
Apr 29, 2022
In December 2021, Shengde Wu’s group from the Department of Urology, Children's Hospital of Chongqing Medical University, published in a paper at Journal of Hazardous Materials, entitled Di-(2-ethylhexyl) phthalate exposure leads to ferroptosis via the HIF-1α/HO-1 signaling pathway in mouse testes. Read More >
Research Trend
How AI + Minigene Aids the Research of Aberrant Alternative Splicing
Apr 26, 2022
Alternative splicing is the regulatory process of selecting different combinations of splice sites within a messenger RNA precursor (pre-mRNA) to produce variably spliced mRNAs. These multiple mRNAs can encode proteins that vary in their sequence and activity and yet all arise from a single gene. Read More >
Research Trend
Fight for Sight - Targeting Genetic Factors of Ophthalmic Diseases
Apr 22, 2022
Genes play a highly significant role in the pathogenesis of eye diseases, some of which are highly prevalent in children and adults. Read More >
Weekly Gene
SYNGAP1-Related Intellectual Disability (MRD5)
Apr 20, 2022
SYNGAP1 (Synaptic Ras GTPase Activating Protein 1) is a Protein Coding gene. The SYNGAP1 gene is located on Chromosome 6 and is responsible for producing the SynGAP protein. Read More >
Research Trend
How Can Lentiviral Vectors Help CGT Research?
Apr 19, 2022
Lentiviruses (LVs) are one of the commonly used delivery vectors for cell and gene therapy, which have been successfully applied to the preparation of CAR-T cells. Read More >
Weekly Gene
Rare Diseases Caused by the CEP290 Gene
Mar 25, 2022
CEP290 (Centrosomal Protein 290) is a Protein Coding gene, encodes a centrosomal protein involved in ciliary assembly and ciliary trafficking. Read More >
Animal breeding
Why Are My Rodents Balding? Learn about Barbering
Mar 07, 2022
Read on to explore why rodent groups barber themselves and each other, the ways this may be prevented, and some common questions and answers about this issue. Read More >
Research Trend
Announcing the Release of Rare Disease Data Center (RDDC)
Mar 04, 2022
In February 2022, the Rare Disease Data Center (RDDC) was officially released to the international research community. Read More >
Research Trend
Induced Pluripotent Stem (iPS) Cells & Gene Editing
Feb 24, 2022
In recent years, the application of CRISPR-mediated gene editing in iPS cells has attracted more and more attention. Read More >