huHSC-NKG-ProM
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
huHSC-NKG-ProM
Product ID
C001544
Gene Name
Background
NKG
Gene Alias
gc; p64; [g]c; CD132; gamma(c)
Classification
Immunodeficient Mouse Models,Humanized Immune System Models
NCBI ID
Phenotype
Chromosome
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Datasheet
Note: When using this mouse strain in a publication, please cite “huHSC-NKG-ProM mice (Catalog C001544) were purchased from Cyagen.”
Strain Description
The huHSC-NKG-ProM mouse is the latest enhanced version of the huHSC-NKG series, where "Pro" indicates the enhanced series and "M" specifically refers to myeloid cells. This mouse utilizes advanced neonate technology and has been process-optimized to allow for the development of lymphoid T cells and B cells, as well as myeloid cells such as monocytes. It is suitable for research on immune checkpoint inhibitors and drugs that target myeloid cells.
Application Area
Tumor Immunology Research: Suitable for drug types such as immune checkpoint inhibitors and those with targets on myeloid cells, for example, combining a PD-1 monoclonal antibody with drugs that affect Macrophage polarization
Autoimmune Disease Research: Evaluation of the pathogenesis of autoimmune diseases and potential therapeutic strategies
Drug Metabolism and Toxicity Research: Assessment of the pharmacokinetic properties and toxic effects of candidate compounds in vivo
Validation Data