huHSC-NKG-ProN
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
huHSC-NKG-ProN
Product ID
C001545
Gene Name
Background
NKG
Gene Alias
gc; p64; [g]c; CD132; gamma(c)
Classification
Immunodeficient Mouse Models,Humanized Immune System Models
NCBI ID
Phenotype
Chromosome
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Datasheet
Note: When using this mouse strain in a publication, please cite “huHSC-NKG-ProN mice (Catalog C001545) were purchased from Cyagen.”
Strain Description
The huHSC-NKG-ProN mouse is the latest enhanced version of the huHSC-NKG series, where "Pro" indicates the enhanced series and "N" specifically refers to NK cells (Natural Killer cells). This mouse utilizes advanced neonate technology and has been process-optimized to allow for the development of lymphoid T cells and B cells, as well as NK cells, with minimal myeloid development. It is suitable for research on immune checkpoint inhibitors, ADCC (Antibody-Dependent Cell-mediated Cytotoxicity) mechanisms, and in vivo CAR-NK cell therapy.
Application Area
Tumor Immunology Research: Suitable for research on immune checkpoint inhibitors, ADCC (Antibody-Dependent Cell-mediated Cytotoxicity) mechanisms, and in vivo CAR-NK cell therapy
Drug Metabolism and Toxicity Research: Assessment of the pharmacokinetic properties and toxic effects of candidate compounds in vivo
Validation Data