B6-hTFRC/hDMD (E49-53)
Product Type
Age
Genotype
Sex
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Basic Information
Model Name
B6-hTFRC/hDMD (E49-53)
Product ID
C001595
Background
C57BL/6NCya
Gene Alias
BMD; CMD3B; MRX85; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46
Classification
Full-Gene Humanized Models,Neurological Disease Models
Chromosome
X
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Note: When using this mouse strain in a publication, please cite “B6-hTFRC/hDMD (E49-53) mice (Catalog C001595) were purchased from Cyagen.”
Strain Description
The B6-hTFRC/hDMD (E49-53) mouse model is a humanized model obtained by breeding B6-hTFRC (CDS) mice (Product No.: C001584) with B6-hDMD (E49-53) mice (Product No.: C001775). This model can be used for research on iron metabolism disorders, Duchenne muscular dystrophy (DMD), neurodegenerative diseases, and tumor development, aiding in the research of TFRC/DMD-targeted drugs.
Application Area
Research on iron metabolism disorders, Duchenne Muscular Dystrophy (DMD), neurodegenerative diseases, and tumor development
Development, screening, and efficacy evaluation of TFRC/DMD-targeted therapies
Research and evaluation of drug delivery across the blood-brain barrier (BBB)
Validation Data