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B6-hTL1A/hIL23A
Product ID:
C001837
Background:
C57BL/6N;6JCya
Documents:
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Basic Information
Model Name
B6-hTL1A/hIL23A
Product ID
C001837
Gene Name
IL23A, TNFSF15
Background
C57BL/6N;6JCya
Gene Alias
P19; SGRF; IL-23; IL-23A; IL23P19; TL1; TL1A; VEGI; TNLG1B; VEGI192A
Classification
Immune Target Humanized Models,Cytokine Humanized Models,Autoimmune Disease Models
NCBI ID
51561, 9966
Phenotype
MGI:1932410, MGI:2180140
Chromosome
--
More
Rare Disease Data Center >>
Document
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Note
Note: When using this mouse strain in a publication, please cite “B6-hTL1A/hIL23A mice (Catalog C001837) were purchased from Cyagen.”
Strain Description
B6-hTL1A/hIL23A mice are humanized models generated by crossing B6-hTL1A (TNFSF15) mice (Catalog No.: C001603) with B6-hIL23A mice (Catalog No.: C001618). These mice are suitable for studying the pathological mechanisms and therapeutic strategies of allergic and inflammatory diseases, immune-related disorders, and cancer, as well as for the screening, development, and preclinical evaluation of TL1A/IL23A-targeted drugs.
Application Area
Area
Screening and development of TL1A/IL23A-targeted therapeutics, and preclinical pharmacodynamic and safety evaluations
Area
Research on the pathological mechanisms and therapeutic strategies for allergic and inflammatory diseases, immune-related disorders, and cancer
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