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huHSC-NKG-hIL15
Product ID:
C001526
Background:
NKG
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Strain Description
The huHSC-NKG-hIL15 mouse refers to an immune system humanized mouse model constructed by transplanting human hematopoietic stem cells (HSC) into NKG-hIL15 mice after sub-lethal dose irradiation. This model can reconstitute various immune cells, has a long lifespan, and is particularly effective in rebuilding human NK cells, which can aid in the development of NK cell-related tumor immunotherapies.
Application Area
Area
Research on the human immune system, haematopoietic system
Area
Human-derived cell line xenograft (CDX) and patient-derived xenograft (PDX)
Area
NK cell development mechanism studies, NK cell-related tumor immunotherapy development, and antibody-dependent NK cell-mediated toxicity (ADCC) studies
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