B6-hIL6/IL6RA
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
B6-hIL6/IL6RA
Product ID
C001607
Gene Name
Background
C57BL/6NCya
Gene Alias
CDF; HGF; HSF; BSF2; IL-6; BSF-2; IFNB2; IFN-beta-2
Classification
Tumor Target Humanized Models,Immune Target Humanized Models,Autoimmune Disease Models
NCBI ID
Phenotype
Chromosome
7
Document
Note: When using this mouse strain in a publication, please cite “B6-hIL6/IL6RA mice (Catalog C001607) were purchased from Cyagen.”
Strain Description
The B6-hIL6/IL6RA mice are a double-gene humanized model obtained by breeding B6-hIL6 mice (Catalog No. C001605) with B6-hIL6RA mice (Catalog No. C001606). This model can be used in researching autoimmune diseases, inflammation-related diseases, cancer, and infectious diseases. It is also useful for the development, screening, and evaluation of IL6/IL6RA-targeted drugs.
Application Area
Research on autoimmune diseases, inflammation-related diseases, cancer, and infectious diseases
Preclinical studies on the development, screening, and evaluation of IL6/IL6RA-targeted drugs
Validation Data