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Animal Models
C57BL/6JCya-Ccnqem1/Cya
Ccnq is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Ccnq knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ccnkem1/Cya
Ccnk is located on chromosome 12 of mice. Nuclease Technology was used to design sgRNA; Ccnk knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ccn4em1/Cya
Ccn4 is located on chromosome 15 of mice. Nuclease Technology was used to design sgRNA; Ccn4 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ccn5em1/Cya
Ccn5 is located on chromosome 2 of mice. Nuclease Technology was used to design sgRNA; Ccn5 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ccnoem1/Cya
Ccno is located on chromosome 13 of mice. Nuclease Technology will be used to design sgRNA; Ccno knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ccn2em1/Cya
Ccn2 is located on chromosome 10 of mice. Nuclease Technology was used to design sgRNA; Ccn2 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ccncem1/Cya
Ccnc is located on chromosome 4 of mice. Nuclease Technology will be used to design sgRNA; Ccnc knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ccnfem1/Cya
Ccnf is located on chromosome 17 of mice. Nuclease Technology will be used to design sgRNA; Ccnf knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ccn3em1/Cya
Ccn3 is located on chromosome 15 of mice. Nuclease Technology will be used to design sgRNA; Ccn3 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ccniem1/Cya
Ccni is located on chromosome 5 of mice. Nuclease Technology will be used to design sgRNA; Ccni knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
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Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)
Key Insights
The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.
  • Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
  • Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
  • Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
  • Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.
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