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Live KO & cKO Mice
As low as $1,111
Shipped in just 2 weeks
Cyagen Knockout Catalog Models
Over 16,000 Strains of KO and cKO Mouse Models | 100% Pure B6 Background | Delivered as Fast as 2 Weeks
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| Summary | Strain Name | C57BL/6J-Psen1em1Cya |
| Strain Symbol | KOCMP-19164-Psen1-B6J-VA | |
| Strain Number | S-KO-03812 | |
| Gene Name | Psen1 (Lethal gene) | |
| Synonyms | Ad3;Ad3h;P;PS;PS-1;PS1;S18;S182 | |
| NCBI Gene ID | 19164 (Lethal gene) | |
| Genetic Background | C57BL/6J | |
| Genetic Modification | Conventional knockout | |
| Description | The Psen1 gene ( NCBI Reference Sequence: XM_006515605 ; Ensembl: ENSMUSG00000019969 ) is located on mouse chromosome 12. Twelve exons are identified , with the ATG start codon in exon 3 and the TAG stop codon in exon 12 (Transcript: ENSMUST00000041806). Exon 4 will be selected as target site. Cas9 and gRNA will be co-injected into fertilized eggs for KO mouse production. | |
| Quality Control | Sperm Quality Evaluation | Pre-cryopreservation: Measurement of sperm concentration, determination of sperm
viability. Post-cryopreservation: A vial of cryopreserved sperms is selected for in-vitro fertilization from each batch. |
| Health Status | SPF | |
| Product Information | Source | Cryopreserved sperm |
| Origin | Cyagen | |
| Region | Global | |
| Strategy Download | Inquire Now |
Ready-to-Use Knockout (KO) and Floxed (cKO) Catalog Models
Cyagen Knockout Catalog Models repository provides a searchable listing of over 16k custom KO and cKO/floxed strains from which live mice are available to researchers in as few as two(2) weeks. Our repository is constantly growing, so feel free to inquire about the status of any specific gene(s) not shown online for more information about pending availability.
Our catalog offers the following advantages compared to a custom model generation
projects:
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Economical
- 100% Pure B6 Background: Eliminates need for backcrossing
- Inexpensive: Cost cannot be beaten by any model generation approach
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Reliable
- Established Lines: eliminate risks associated with model generation
- Guaranteed Models: validated genotyping data available upon request
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Efficient
- Deliverables: ≥3 HET mice in as fast as 2 weeks
- Reduced Paperwork: Inquire online to place an order
