If your lab is working on research projects that utilize mouse/rat models, off-the-shelf models often come with limitations that may be addressed through genomic modifications to improve homology. Oftentimes, desired strain information may be available through catalogs & archives, but obtaining model specimens may be far more challenging for niche studies. Cyagen offers free project strategy consultation with our experts to generate custom models to your specification – allowing you to create the perfect model for your study and lead the way for model organism research.

Cyagen is AAALAC accredited, OLAW assured, and features SPF-free animals. More detailed information about our facilities and our Animal Health and Animal Welfare Program is available on our website. With over 10 years’ experience, competitive pricing, and money back guarantees, it's easy to see why researchers around the world feel secure when ordering from Cyagen – our client testimonials speak for themselves.

Our custom animal model generation services include:

Mouse Models

Rat Models

TurboKnockout® (conditional KO/KI)

CRISPR large fragment KI (any locus)

CRISPR large fragment KI (any locus)

CRISPR ROSA26 KI

CRISPR ROSA26 KI

CRISPR point mutations

CRISPR point mutations

CRISPR knockouts

CRISPR knockouts

Transgenics (plasmid/BAC based)

Transgenics (plasmid/BAC based)

PiggyBac transgenics

PiggyBac transgenics

PiggyBac-on-BAC transgenics

PiggyBac-on-BAC transgenics

 

Transgenic embryos (plasmid/BAC based)

 

PiggyBac transgenic embryos

 

With our expertise and a wide range of proven genetic engineering methodologies, we can guarantee generation of complicated models, including: constitutive KO/KI, conditional KO/KI, humanized mice, megabase deletion, point mutations, overexpression models, and more.  Our TurboKnockout® service uses a proprietary ES cell mediated gene targeting method to eliminate two (2) generations of breeding, shortening production time by 4-6 months. For consistent expression of a transgene, our proprietary PiggyBac services deliver single-copy transgenic mice – preventing loss of the transgene sequence due to insertion of multiple copies. Cyagen's experts have generated thousands of models and offer 100% money back guarantee - no animals, no charge.

If you have any questions or would like any assistance with a project strategy, please contact us and we will be happy to assist you.

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