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Research Trends
JAK2V617F Mutant Mouse Model: A Robust Tool for Myeloproliferative Neoplasm Research
Dec 06, 2024
Are you looking to advance your understanding of myeloproliferative neoplasms (MPNs) and their genetic underpinnings? Read More >
Research Trends
VEGFA Humanized and Transgenic Mice: Empowering Ophthalmology & Oncology Drug Development
Nov 29, 2024
How do we bridge the gap between preclinical research and breakthrough therapies for retinal diseases and cancer? Read More >
Research Trends
Humanized Tau Protein Mouse Models to Accelerate Alzheimer's Drug Development
Nov 22, 2024
Alzheimer’s disease (AD) drug development continues to face challenges in 2024, with recent failures highlighting the need for new approaches targeting Tau protein. Read More >
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Inducible Cre & Fluorescent Reporter Mouse Model for Obesity Research: Agrp-IRES-CreERT2-P2A-tdTomato Mice
Nov 08, 2024
Obesity and hunger are two closely related physiological states involving complex neural and hormonal regulatory mechanisms. Read More >
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B6-Igl Knockout Mice: Research Model for B Cell Development & Antibody Diversity
Oct 31, 2024
The novel B6-Igl Knockout (KO) mouse model exclusively expresses κ light chain immunoglobulins, offering researchers a powerful tool for exploring B cell development and antibody diversity. Read More >
Research Trends
USH2A Humanized Disease Model for Usher Syndrome Type II Research
Oct 25, 2024
Usher Syndrome (USH) is a genetic disorder that causes both hearing and vision loss due to mutations in genes which play a critical role in inner ear and retinal function. Read More >
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Familial Dysautonomia (FD) Humanized Disease Models: ELP1 & ELP1 IVS20+6T>C
Oct 18, 2024
With the advancement of whole-genome sequencing, it has become increasingly recognized that intronic mutations play a significant role in various diseases, particularly rare diseases. Read More >
Research Trends
Hep G2 Cell Line: Liver Cancer Research Applications with Gene Editing & CDX Tumor Models
Oct 10, 2024
Explore Hep G2 cell line applications in liver cancer research, gene editing using Smart-Targeted Gene Editing™, and subcutaneous xenograft (CDX) tumor models. Discover best practices for cell culture, gene editing services, and tumor modeling. Read More >
Research Trends
HSD17B13 Humanized Mouse Model: A Breakthrough Tool for MASLD and RNAi Therapy Research
Sep 27, 2024
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a complex, multifactorial condition that has become a leading cause of liver-related morbidity and mortality. Read More >
Research Trends
How the B6-hTGFBI Humanized Mouse Model is Advancing Corneal Dystrophy Research
Sep 23, 2024
Corneal dystrophy (CD) is a group of rare hereditary disorders caused by abnormal deposits of substances in the cornea. Read More >