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Research Trends
High-Quality Adeno-Associated Virus (AAV) Packaging
Dec 04, 2023
In the rapidly advancing field of gene therapy, the efficiency and reliability of adeno-associated virus (AAV) vectors play a pivotal role in driving groundbreaking research and therapeutic developments. At Cyagen, we stand at the forefront of this revolution, offering a comprehensive suite of AI-assisted AAV production services designed to streamline your experimental process and elevate your research to new heights. Our commitment to excellence extends across the entire spectrum of AAV production, from vector design and construction to virus packaging, purification, expression analysis, and functional validation. Read More >
Research Trends
Ensuring Optimal Well-being for Lab Mice: A Guide to Daily Observation and Care
Nov 21, 2023
In the realm of biomedical research, mice are widely used for various experiments. To guarantee their well-being and enhance the precision of experiments, it is imperative to dedicate time and attention to their daily care. This article delves into the nuances of maintaining mouse health, shedding light on key aspects of daily care and observation that significantly impact the success of scientific endeavors. Read More >
Research Trends
What are rare immunological diseases? Exploring the Advantages of NKG Severe Immunodeficient Mice
Nov 03, 2023
Do you recall the famous "Bubble Boy"? Poor David suffered from Severe Combined Immunodeficiency (SCID), which made him incapable of combatting any bacteria or viruses, forcing him to spend his entire life in a sterile environment. Shortly after his birth, doctors placed him into a sterile bubble, hence the term "Bubble Boy" for people with similar conditions. Today, let's delve deeper into immunodeficiency disorders. Read More >
Research Trends
Congenital Genetic Abnormalities & Related Phenotypes in Rat Models of Human Diseases
Oct 27, 2023
In addition to factors related to routine husbandry practices, rats are also susceptible to various genetic diseases, known as congenital genetic abnormalities. Today, we will introduce some congenital genetic abnormalities commonly seen in rats. Read More >
Research Trends
Maintaining Rat Colony Health: A Guide to Non-infectious Diseases in Rats
Oct 17, 2023
Disease prevention, daily care and experimental procedures for rats are vital for the well-being and health of rats. Today, we will introduce some non-infectious diseases that affect rats, across the categories of genetic predisposition to disease, nutritional disorders, colony management-related disorders, and iatrogenic (injury-related) illnesses. Read More >
Research Trends
Taking a Closer Look at Common Animal Models for Tumor Diseases: Colorectal Cancer
Sep 28, 2023
Colorectal cancer is a common malignancy that occurs in the colon, a part of the digestive tract. It is typically found at the junction of the rectum and sigmoid colon and has the highest incidence in the 40 to 50-year-old age group. Read More >
Research Trends
Rare Diseases Are Not Rare: The Mechanistic Research on Kennedy Disease (KD)
Sep 22, 2023
Kennedy disease (KD), also known as Spinal and Bulbar Muscular Atrophy (SBMA), is a recessive, X-linked, adult-onset motor neuron disease characterized by the slow, progressive weakness of the bulbar and limb muscles. Kennedy disease predominantly affects adult males, with an estimated global incidence of 1-2/100,000. Read More >
Research Trends
Do not give up chasing the light—Gene therapy aids the blind in regaining their sight
Sep 19, 2023
It is said that the eyes are the windows to the soul, but there are many people with congenital blindness who cannot "see" the light. According to publicly available data from the World Health Organization, there are at least 2.2 billion people globally with impaired vision or blindness. Read More >
Research Trends
Exploring the Power of the Cre-Lox System: Conditional Gene Targeting in Mice for In Vivo Applications
Sep 08, 2023
Conditional gene targeting in mice has revolutionized the field of molecular biology and genetic engineering. In vivo applications of the Cre-lox system are highly efficient, specific, and versatile. The Cre-lox system is a powerful tool to manipulate and study gene function in vivo, and it relies on the Cre recombinase enzyme to induce site-specific recombination between two LoxP sites. Read More >
Research Trends
What is Familial Exudative Vitreoretinopathy (FEVR)? What are the mouse models for it?
Aug 31, 2023
Familial Exudative Vitreoretinopathy (FEVR) is a group of rare hereditary retinal disorders characterized by abnormal retinal vascular development, leading to incomplete peripheral retinal vascularization and subsequent retinal ischemia. Read More >