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The Molecular Biology Revolution
Jul 31, 2015
In an era of designer mice and complex multi-component DNA constructs, it is difficult to imagine that there was a time (not so long ago) when biologists lacked... Read More >
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Virus Variations
Jun 23, 2015
Virus transduction is a common method used to introduce new genetic material into cells. Since the first use of a viral vector on mammalian cells in the 1970's... Read More >
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Super Mice
May 14, 2015
Superheroes are a pop culture phenomenon. Their amazing abilities entertain and inspire us, but hardly seem attainable in the real world. However, superpowers... Read More >
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CRISPR versus HIV
Apr 14, 2015
HIV infection affects more than 35 million people worldwide. Over the past three decades, progress has been made in HIV treatment, mostly through the use of... Read More >
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The rat choice for your experiments
Mar 14, 2015
For more than a century, rodents have played a pivotal role in biomedical research, and provided experimental systems for investigating mammalian biology... Read More >
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Humanized alleles in animal models
Feb 14, 2015
Animal models play a vital role in modern biomedical research. In particular, mouse and rats are profoundly important. However, mice and rats are imperfect... Read More >
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Choosing a system for in vivo genome editing: Is TALEN or CRISPR-Pro best for your project?
Jan 01, 2015
The gold standard for genetically engineering mouse models is ES-cell based homologous recombination. However, this approach is very time-consuming... Read More >