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COVID-19
Complete Collection: The Hottest Mouse Models for Coronavirus Research
Apr 10, 2020
The World Health Organization (WHO) announced the reclassification of the COVID-19 outbreak as a global pandemic on March 11, 2020. With the rapid spread of the disease across the globe, countries worldwide have joined the war against the SARS-CoV-2 virus, for which, early prevention, control, and treatment may provide valuable tools against the pandemic. Read More >
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Research Trend
Applications of Sirtuins (SIRT) Knockout Mouse Models in Disease Research
Apr 07, 2020
Sirtuins - colloquially known as the longevity genes – are a highly conserved family of NAD1+-dependent enzymes which are involved in the regulation of gene silencing, metabolism, cell division, apoptosis, and genetic material repair. Additionally, it has been reported that sirtuins play important roles in the development of multi-systemic diseases. Read More >
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Research Trend
COVID-19
Beyond Mediating Host Cell Entry of SARS-CoV-2: What Roles Does ACE2 Play?
Apr 01, 2020
In our fight against the virus and COVID-19, researchers have studied the SARS-CoV-2 virus itself and its host receptor, ACE2, from the aspects of epidemiology, pathology, virus traceability, prevention, and control measures. The human ACE2 receptor is known to interact with SARS-CoV-2 and permit its initial cell entry, making it particularly important to explore its function. Read More >
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Virtual Consultations for Custom Animal Model Solutions
Mar 31, 2020
With the emergence of the novel coronavirus (SARS-CoV-2), the meetings, shows, and conferences that allow us to interface with customers in person have been canceled for the foreseeable future. Both the Cyagen US and Taconic Biosciences' Model Design Specialist teams are working remotely from home to help do our part to flatten the curve. Read More >
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Research Trend
How to Choose the Right Mouse Models and Genetic Modification Method for Your Research
Mar 30, 2020
Our experts put together the following advice on how to choose the most suitable mouse strains & genetic modification techniques for your research. In practical applications, it is necessary to select mouse strain backgrounds that align with your desired research applications to achieve good experimental results. Read More >
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Breaking News
Expanded Knockout Catalog Models – Over 10k Genes Now Available
Mar 24, 2020
In our continuing efforts to expand the gene knockout models offered in the Cyagen Knockout Catalog, described in our recent Technical Bulletin, we are proud to announce the availability of over 10,000 KO mouse models. Read More >
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ROSA26: The ‘Safe Harbor’ Locus in the Mouse Genome
Mar 23, 2020
What is the first thing that comes to your mind when we mention ‘safe harbor’? The ‘safe harbor’ we want to talk about today is not the kind for ships, but, rather, the safe locus for targeted integration of exogenous gene in the mouse genome. Let's explore one of the most well-established safe loci in the mouse genome - ROSA26. Read More >
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COVID-19
Interview: Impact of COVID-19 Respiratory Illness on the Life Science Research Industry
Mar 20, 2020
With the gradual improvement of the COVID-19 situation in China in the past few days, along with a worsening situation across many regions, research on vaccines and related antiviral drugs has become a key issue for most people both inside and outside the life science research industry. Read More >
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Research Trend
COVID-19
Cytokine Storm: The New Perspective for COVID-19 Research
Mar 19, 2020
Since COVID-19 poses a significant threat to public health and also represents a challenge for antiviral drug development and administration globally, current efforts focus on prevention and control while accelerating the research on the SARS-CoV-2 coronavirus, which has caused the outbreak of COVID-19. Read More >
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CRISPR-Pro Versus ES Cell Targeting：Which is the Optimal Solution?
Mar 19, 2020
With the rapid advancement of biomedical technology in recent years, customized treatment methods such as targeted medicine, immunotherapy, and gene therapy have become the main directions of biomedical innovation - which is intimately related to the development of gene-editing technology. Read More >