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Research Trend
Application of CRISPR-Pro Gene Editing in CAR-T Cell Immunotherapy
Dec 29, 2021
The principle of CAR-T cell immunotherapy is to use genetic engineering methods to express chimeric antigen receptor (CAR) molecules on the surface of T cells. Read More >
Research Trend
Gene Therapy for Cardiovascular Disease: Application of Adeno-associated Viral Vector (AAV)
Dec 24, 2021
As of this year, there have been hundreds of recombinant adeno-associated virus (rAAV) gene therapy products approved to be marketed and entered into clinical trials worldwide. Why does AAV vector have such potential? Read More >
Research Trend
How to Validate Your CRISPR Knockout Cell Line?
Dec 20, 2021
When establishing a CRISPR-Pro-based knockout (KO) cell line model, it is important to validate the genetic modifications which have occurred. Read More >
Research Trend
How to Make A Lentiviral Overexpression Vector?
Dec 07, 2021
If you want to effectively achieve gene up-regulation or knockdown, constructing an overexpression stable cell line through lentiviral transfection will be your best choice. Read More >
Research Trend
Do You Know About Gene Therapy Research?
Dec 01, 2021
What is Gene Therapy? Gene therapy aims to treat or cure genetic diseases through the introduction of foreign, normally-functioning genes into target cells to correct or compensate for defective or abnormal genes. Read More >
Research Trend
Uses of Humanized Mice in Tumor Immunotherapy Study
Nov 30, 2021
A PDX humanized mouse is engrafted with a human tumor, which we call a patient-derived xenograft (PDX). Read More >
Research Trend
How Are Humanized Mice Made?
Nov 24, 2021
Humanized mice — engrafted with human tissues, cells, and/or genes — are a model for studying preclinical aspects of human ailments. Read More >
Latest Discovery
Research Trend
LARP7-Mediated U6 snRNA Modification and Its Role in Pre-mRNA Splicing As Well As Its Functions in Mouse Spermatogenesis
May 11, 2021
In higher eukaryotes, most genes co Read More >
Research Trend
Research Process of Parkinson’s Disease
May 10, 2021
PD ranks second among neurodegenerative diseases. The most well-known symptom of PD is involuntary tremors, characterized by uncontrolled shaking, most notably in the hands. Another important symptom is the weakening of balance ability, but it should be noted that the weakening of balance has nothing to do with cerebellar injury. Read More >
Newsletter
Research Trend
Cyagen Conditional Knockout Mouse Model Publication Alert
Apr 29, 2021
The following publications demonstrate the use of conditional knockout mouse models across a range of human disease research fields, including immunology, cardiology, metabolomics, oncology and more. Read More >