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Fight for Sight - Targeting Genetic Factors of Ophthalmic Diseases
Apr 22, 2022
Genes play a highly significant role in the pathogenesis of eye diseases, some of which are highly prevalent in children and adults. Read More >
Research Trend
How Can Lentiviral Vectors Help CGT Research?
Apr 19, 2022
Lentiviruses (LVs) are one of the commonly used delivery vectors for cell and gene therapy, which have been successfully applied to the preparation of CAR-T cells. Read More >
Research Trend
Announcing the Release of Rare Disease Data Center (RDDC)
Mar 04, 2022
In February 2022, the Rare Disease Data Center (RDDC) was officially released to the international research community. Read More >
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Induced Pluripotent Stem (iPS) Cells & Gene Editing
Feb 24, 2022
In recent years, the application of CRISPR-mediated gene editing in iPS cells has attracted more and more attention. Read More >
Research Trend
Inducible Humanized ACE2 Mouse Model For Coronavirus (COVID-19) Research
Feb 15, 2022
The newly-developed K18 promoter-driven hACE2-Cre-ERT2 knock-in (hACE2 KI) mouse model with a C57BL/6J background provides an additional platform for continued research. Read More >
Research Trend
Analyzing the Process of CAR T-Cell Therapy Research
Feb 10, 2022
This article focuses on the process of developing CAR T-cell therapy and discusses the importance of each preclinical and clinical stage in the research of CAR T-cell therapy. Read More >
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Application of AAV-mediated Gene Therapy in Metabolic Disorders
Jan 24, 2022
The application of recombinant Adeno-Associated Virus (rAAV) drugs in clinical trials of metabolic diseases around the world is mainly concentrated among the following indications Read More >
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Application of Gene Therapy in Mucopolysaccharidosis IVA (MPS IVA) (Part B)
Jan 20, 2022
In Part A, we describe how the Mucopolysaccharidosis IVA (MPS IVA, MPSIVA) rat model is generated. Please see Part B which we explore other promising applications of  AAV9-Galns treatments. Read More >
Research Trend
The Ultimate Guide to Humanized Mice for Antibody Research
Jan 13, 2022
With the development of research on the impact of immunity and inflammation on cancer, the performance of humanized mice attract tremendous attention in cancer clinical research. Read More >
Research Trend
Application of Gene Therapy in Mucopolysaccharidosis IVA (MPS IVA) (Part A)
Jan 12, 2022
Mucopolysaccharidosis IVA (MPS IVA) - also known as Morquio Syndrome, type A - is inherited in an autosomal recessive manner and caused by mutations in the GALNS gene. Read More >