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Research Trends
Y Maze Behavioral Task: Studying the function of spatial learning and memory in Neuroscience research
Dec 29, 2022
Since animals can't speak, they can't tell you whether they remember what just happened, or what they are experiencing at this moment. The most direct way to understand what they are thinking is to observe their behaviors. Read More >
Research Trends
A Good Helper for SARS-CoV-2 & COVID-19 Research: Selection and Application of Mouse Models
Dec 06, 2022
Animal models have assisted researchers' understanding of COVID-19 pathogenesis and host immune response to SARS-CoV-2 infection, and are of great significance in helping the rapid development of disease preventatives, vaccines, and treatments. Read More >
Research Trends
Application of Flow Cytometry in Preclinical CAR-T Development
Nov 28, 2022
Chimeric Antigen Receptor T-Cell (CAR-T) Immunotherapy uses genetic engineering technology to transform autologous or allogeneic T cells into new killer cells targeting tumor-specific antigens, by which remarkable results have been achieved in the treatment of hematological malignancies. Read More >
Research Trends
Animal Welfare Focus: Humane Endpoints in Rats and Mice in Tumor Research Programs
Nov 04, 2022
In recent years, more and more people advocate the "3Rs" principle of experimental animals: Reduction, Replacement, and Refinement. Read More >
Research Trends
Vision Stolen by Years - Age-related Macular Degeneration
Oct 26, 2022
Many older adults experience a noticeable loss of vision as age increases, but the inability to see fine details in the center of vision may be a sign of age-related macular degeneration (AMD). Read More >
Research Trends
Accelerating CAR-T Cell Therapy Research
Oct 13, 2022
By using the body's own immune system to kill tumor cells, immune cell therapy is anticipated to be a breakthrough strategy to "cure" many types of cancer. Among them, chimeric antigen receptor T-cell immunotherapy (CAR-T) has achieved remarkable results in the treatment of various hematological malignancies. As of 2022, seven CAR-T cell therapy products have been launched globally, including three in China. Read More >
Research Trends
Research Progress of CAR-T Therapy in Solid Tumor Treatment
Sep 23, 2022
CAR-T cell therapy research has developed rapidly in recent years, largely based on the remarkable efficacy of CAR-T therapy in hematological malignancies, and scientists are moving quickly to apply this innovative immunotherapy to the treatment of solid tumors, including sarcomas, carcinomas, and lymphomas. Herein, we review the background of CAR-T cell therapy in solid tumor treatment, common research targets, CAR-T optimization strategy, and clinical research progress. Read More >
Research Trends
A Study on The Mechanism of Achromatopsia
Sep 15, 2022
Patients with achromatopsia (ACHM) have abnormal color discrimination on the three color vision axes corresponding to the three cone cells. The patient's three cones, which sense red, green and blue, are completely inoperative, so they cannot distinguish between different colors. Read More >
Research Trends
CRISPR-Pro-Mediated Gene Editing System for Effective Treatment of X-linked Retinitis Pigmentosa
Aug 09, 2022
Mutations in the retinitis pigmentosa GTPase regulator (RPGR) gene are associated with X-linked retinitis pigmentosa (XLRP), which accounts for 10% to 20% of all cases of retinitis pigmentosa (RP) and is one of its most severe forms. Herein, we review the research procedure that has culminated in the development of a potential gene therapy for XLRP caused by RPGR mutations. Read More >
Research Trends
Why CAR NK Cell Therapy Research Is Quickly Growing
Aug 05, 2022
What is CAR-T? The full name of CAR here is Chimeric Antigen Receptor, its structure includes extracellular domain, transmembrane domain, and an intracellular signal domain. Read More >