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Research Trend
Introduction to the Cre-Lox Recombination System
Oct 20, 2020
With the advantages of simple operation and high recombination rate, the Cre-Lox system has now become a powerful tool for genetic manipulation across in vivo and in vitro. The Cre-Lox system enables gene expression with exceptional spatial (expresses a gene in specific cells, tissues, or entire organisms) and temporal (at specific time points through the application of the Cre-Lox system) control. Read More >
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Breaking News
Conditional Knockout (Floxed) Mice Now Available from Cyagen Knockout Catalog Models
Oct 19, 2020
In March 2020, Cyagen officially launched the Cyagen Knockout Catalog Models repository – which has provided researchers in the Americas and Europe with ready to use knockout (KO) mouse models in as few as three (3) months. To date, we have cryopreserved sperm from over 10k KO mouse strains to offer affordable, established, and rapidly available KO models to both research institutions and pharmaceutical corporations. Read More >
Newsletter
Entry Tips for the Taconic-Cyagen Custom Animal Model Awards (CAMA) Grant Competition
Oct 02, 2020
The goal of the Taconic-Cyagen Cyagen Animal Model Awards (CAMA) is to support high-value biomedical research projects that utilize mouse or rat. This competition will offer a range of grant awards, collectively valued at over $77,350, that will help fund custom animal model (CAM) projects that will bring the most impact to their respective research fields. Read More >
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Research Trend
Conditional Rat Models for Human Disease Research
Sep 21, 2020
Rats are an ideal animal model for human disease research – compared to mice, rats are physiologically, morphologically, and genetically closer to humans – as covered in our recent Technical Bulletin. Since the first targeted knockout (KO) rat was developed in 2010, significant progress has been made in their use as experimental model animals in basic research, drug screenings, and preclinical drug evaluations. Read More >
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Research Trend
Rats - The Animal Model that is Revitalizing Medical Research
Sep 09, 2020
Establishing appropriate animal models of disease is of vital importance in basic medical research – for which, rats and mice have become the animals of choice. Mice are considered the most important model animal for analyzing human gene functions due to its small size, low operational costs, relatively stable embryonic cells, and pliability for various genetic manipulations and gene editing. Read More >
Research Trend
COVID-19
Research Progress on SARS-CoV-2 Neutralizing Antibody and Vaccines
Aug 31, 2020
Though the current situation regarding COVID-19 is still severe, since July, many successes have been achieved on SARS-CoV-2 neutralizing antibody and Phase II clinical trials of SARS-CoV-2 vaccines. With the effort of scientists worldwide, results indicate that research will continue to make progress in the fight against COVID-19. Read More >
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Research Trend
COVID-19
ACE2 Catalog Models – Humanized, Conditional Knockin, and Knockout Mice
Aug 27, 2020
As the leading provider of custom animal model generation services, Cyagen’s R&D team began developing mouse models for studying the novel coronavirus in the early stages of the COVID-19 outbreak. Read More >
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Research Trend
Latest Discovery
RALY Gene Feature: New Implications in Metabolism and Cholesterogenesis
Aug 18, 2020
The heterogenous nuclear ribonucleoprotein (hnRNP) family are multifunctional complexes of RNA and protein present in the cell nucleus that serve critical roles in gene regulation. Multiple lines of evidence have linked hnRNP abnormalities as key pathobiological drivers of cancer and neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Read More >
Newsletter
Rare Disease Grant Awards Announced for BeHEARD Challenge
Aug 11, 2020
Cyagen Biosciences recently announced our participation as a technology award sponsor for the 2019-2020 BeHEARD Rare Disease Science Challenge, hosted by the Rare Genomics Institute. Now that the competition has concluded, we are excited to release details regarding the winners of the technology awards and the rare disease studies they plan to pursue with their prizes. Read More >
Newsletter
Cyagen’s Checklist for Your Return to the Lab
Jul 31, 2020
As scientists around the world continue to grapple with the implications of COVID-19 on their research, Cyagen remains available to assist with all your needs for in vivo model services and products. Our expert support team understands that researchers worldwide are up against many different barriers in starting their projects. Read More >